The science of caffeine and paracetamol

Paracetamol exerts its analgesic and antipyretic effect by inhibition of prostaglandins.1 On the other hand, the antagonism of adenosine receptors and inhibition of cyclo-oxygenase activity at some sites may explain caffeine’s adjuvant properties.2,4

Paracetamol chemical structure

Paracetamol basics

Paracetamol or acetaminophen is one of the most used analgesic and antipyretic over-the-counter drugs globally.1

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Do you know that contrary to popular believe, caffeine is not considered an addictive compound?3

Discover the Panadol range with paracetamol and caffeine

Panadol Extra pack shot

Panadol Extra

With a dual “active” formulation that fights tough pains such as headaches,5,6 migraines,7 dental pain8 and menstrual pain.9

Panadol Migraine pack shot

Panadol Migraine

A powerful over-the-counter triple action analgesic containing paracetamol, acetylsalicylic acid (aspirin) and caffeine that targets major symptoms (photophobia, phonophobia, nausea and pain) of migraine with or without aura.10

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Woman with migraine

Headaches and migraines

Learn more about headaches and migraines.

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Patient care resources

Patient care resources

An easy to use tool for pain assessment in your patients or customers.

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Request samples

Request Samples

Provide your patients with a product sample when you make your expert recommendation to encourage them to make changes for better oral health and pain relief.

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